Midlife cardiovascular fitness and dementia
نویسندگان
چکیده
منابع مشابه
Midlife Pulse Pressure and Incidence of Dementia
Background and Purpose—Previous studies have shown that midlife systolic blood pressure (SBP) predicts late-life cognitive decline and incident dementia. This study explores whether this association is attributable to the pulsatile, ie, pulse pressure (PP), or the nonpulsatile component of blood pressure (BP). Methods—Data are from the Honolulu-Asia Aging Study, a community-based study of Japan...
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BACKGROUND While high adiposity in middle age appears to be related to greater dementia risk, studies exploring this association in the elderly are conflicting. OBJECTIVE To evaluate associations between midlife and late-life obesity and risk of dementia. DESIGN Prospective study with mean follow-up of 5.4 years (1992-1994 through 1999). SETTING Community-dwelling sample in 4 US sites rec...
متن کاملAssociation Between Midlife Cardiorespiratory Fitness and Risk of Stroke
Stroke remains one of the leading causes of morbidity and mortality. In the United States, stroke remains the third leading cause of death and a common reason for hospitalization, accounting for >$28 billion in direct medical costs annually. Several previous studies have demonstrated an inverse relationship between cardiorespiratory fitness (CRF) and both fatal and nonfatal stroke. However, the...
متن کاملCardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
OBJECTIVE A study was undertaken to determine whether better cognitive functioning at midlife among more physically fit individuals reflects neuroprotection, by which fitness protects against age-related cognitive decline, or neuroselection, by which children with higher cognitive functioning select more active lifestyles. METHODS Children in the Dunedin Longitudinal Study (N = 1,037) complet...
متن کاملRising Midlife Obesity Will Worsen Future Prevalence of Dementia
BACKGROUND Midlife body weight status has been found to affect late life dementia outcomes. A cohort projections model was developed to assess the impact of midlife body mass index (BMI) profile on dementia in older Australians. METHODS A baseline projection using age-sex specific dementia prevalence rates was constructed and the results of scenarios that took account of midlife BMI were comp...
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ژورنال
عنوان ژورنال: Neurology
سال: 2018
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000005290